Prop Bets: Los Angeles Rams VS San Francisco 49ers 2025-11-09

Rams vs. 49ers: A Tale of Two Title Hopes (With a Side of Props)
The Los Angeles Rams (-5.5, implied probability: ~52-53%) and San Francisco 49ers (+5.5, 47-48%) clash in a Week 10 showdown that’s less “title race” and more “don’t embarrass your QB.” The Rams, riding a three-game winning streak, are favored to avoid a home-team collapse at Levi’s Stadium. The 49ers, meanwhile, haven’t back-to-back wins since their season-opening romp—probably because their schedule includes one of the NFL’s top defenses, which is also named “Los Angeles Rams.”

Key Stats to Know:
- Rams’ Matthew Stafford has thrown just 2 interceptions all season. His “UNDER 0.5 interceptions” prop (+33% implied probability at -141 odds) is a bet for the faint of heart—or anyone who’s seen him torch the 49ers for 389 yards and 3 TDs in Week 5.
- George Kittle (49ers) has 12 catches in 4 games. His “UNDER 4.5 receptions” line (-119) is basically a math problem: How many ways can you limit a guy with 3 TDs in 8 games to fewer than 5 catches? Answer: A lot.
- Kyren Williams (Rams) is an anytime TD scorer at +100 odds (50% implied probability). He’s scored in 4 straight games, including a Saints-slaying last week. If he doesn’t touch the ball 20 times, is it even a real NFL game?

Odds Breakdown:
- Moneyline: Rams at -150 (60% implied), 49ers at +130 (43.5%).
- Spread: Rams -5.5 (52-53%), 49ers +5.5 (47-48%).
- Total: 49.5 points, even money on Over/Under. With both teams’ defenses playing “let’s trade field goals,” the Over might as well be a bet on whether the halftime show will include a marching band.

Prop Bet Pick of the Day:
Take Stafford UNDER 0.5 interceptions. Why? Because the 49ers’ defense is like a group of librarians trying to tackle a bull: well-intentioned, but not exactly built for chaos.

Final Prediction:
The Rams cover the spread (-5.5) and win outright, while Williams scores a TD just to keep the props interesting. The 49ers will either throw a Hail Mary or a Hail Mary to the sportsbooks for letting them set such generous lines.

Bet with caution, and never trust a team that can’t spell “back-to-back.” 🏈

Created: Nov. 9, 2025, 4:02 p.m. GMT